NASA SBIR 2006 Solicitation


PROPOSAL NUMBER:06 X14.01-8254
SUBTOPIC TITLE:Health Preservation in the Space Environment
PROPOSAL TITLE:Novel Versatile Intelligent Drug Delivery

SMALL BUSINESS CONCERN (Firm Name, Mail Address, City/State/Zip, Phone)
Tesla Laboratories
2711 Jefferson Davis Hwy, Suite 200
Arlington, VA 22202-4015
(414) 807-0006

PRINCIPAL INVESTIGATOR/PROJECT MANAGER (Name, E-mail, Mail Address, City/State/Zip, Phone)
Patrick I James
3666 Chase Court
Boulder, CO  22202-4015
(303) 554-5769

TECHNICAL ABSTRACT ( Limit 2000 characters, approximately 200 words)
This SBIR project will demonstrate and develop a novel micro-pump capable of controlled and selective chemical transport. Phase I will create, characterize, and model a robust and readily fabricated low-power miniaturized pump achieving "forceless" dissolved ion transport compatible with microgravity conditions. The compact technology will be extremely versatile, low-cost, stable, easily tailorable, and readily scaleable to higher fluxes via structure duplication and application in parallel. The device will be physically stable, chemically inert, and pH insensitive while its small dimensions result in lower power consumption and reduced mass. The result will be a more versatile and general pump capable of moving a variety of drugs. Phase I will explore the pump performance, stability, and design optimization using selected ionic compounds as model transport subjects by running designed experiments exploring pump operations as a function of key pump structural and operation variables. This data will determine the controlling variables, their effects on the system performance, and will be utilized with first-principles system physics analysis to develop a pump operation model. This model will allow rapid technology configuration exploration, operation performance refinement, and will provide critical insights into preferred, better optimized, structures to be evaluated during Phase II.

POTENTIAL NASA COMMERCIAL APPLICATIONS ( Limit 1500 characters, approximately 150 words)
This technology could benefit NASA by providing smaller, lower power, microgravity compatible pumps for safe and reliable intelligent drug delivery. It could also assist resource recovery/generation or waste disposal/processing through controlled water and mineral reclamation. Additionally it could enhance on-site process and synthesis control, product purification, and fuel cell operation.

POTENTIAL NON-NASA COMMERCIAL APPLICATIONS ( Limit 1500 characters, approximately 150 words)
Mature technology should find widespread industrial utility in small scale pumping and micro-actuator operation, separation of mixed charged species, fine chemical synthesis/purification, feedback controlled drug delivery, and sensor enhancement through selective preconcentration for example. Additionally, this technology could provide the basis for artificial muscle and/or nerve cell development.

NASA's technology taxonomy has been developed by the SBIR-STTR program to disseminate awareness of proposed and awarded R/R&D in the agency. It is a listing of over 100 technologies, sorted into broad categories, of interest to NASA.

Biomedical and Life Support
Biomolecular Sensors
Waste Processing and Reclamation

Form Printed on 09-08-06 18:19