NASA SBIR 2004 Solicitation

FORM B - PROPOSAL SUMMARY


PROPOSAL NUMBER:04-II B3.03-9533
PHASE-I CONTRACT NUMBER: NNJ05JB78C
SUBTOPIC TITLE:Human Adaptation and Countermeasures
PROPOSAL TITLE:Compact Transcranial Doppler (TCD) for Bioastronautics Research

SMALL BUSINESS CONCERN (Firm Name, Mail Address, City/State/Zip, Phone)
Genexpress Informatics Inc.
13091 Ponds Springs Road, Suite 150
Austin ,TX 78729 - 6442
(512) 219 - 8588

PRINCIPAL INVESTIGATOR/PROJECT MANAGER (Name, E-mail, Mail Address, City/State/Zip, Phone)
Robert   Chin
rchin@genexpressinfo.com
13091 Ponds Springs Road, Suite 150
Austin, TX  78729 -6442
(512) 219 - 8588

TECHNICAL ABSTRACT (Limit 2000 characters, approximately 200 words)
Returning men to the Moon and manned Mars missions will require advanced bioastronanutics research. One possible risk is Decompression Sickness (DCS) resulting from extravehicular activity (EVA), after exposure to habitat conditions that would be generated using available Moon or Martian resources. A key research tool to measure the onset of DCS is a Transcranial Doppler (TCD) instrument. The present research tool is bulky and does not allow for measurement of the TDC signal under astronaut stress conditions including exercise, EVA, pre-breathing prior to EVA, and work.

GeneXpress Informatics, Ten X Technology and UTHSC-SA proposes to develop a fully functional TCD research device for hypobaric experiments for determining DCS risk assessment and management. GXI has develop a unique auto-focusing and steering TDC system which allows for the real time monitoring of DCS parameters during hypobaric stress activity experiments. In this Phase II program, the team proposes to (1) Define and Determine test bed requirements, (2) Identify and procure TCD components, (3) Design & Assemble the Piezoelectric Transducer, (3) Design & assemble Transducer attachment method, (4) Design, Assemble & Test Portable Instrument Electronics, (5) Develop Software for the Instrument and Development Platform, (5) Evaluate Laboratory Test Bed, and (6) Construct System Deliverable.

POTENTIAL NASA COMMERCIAL APPLICATIONS (Limit 1500 characters, approximately 150 words)
Advanced spaceflights will possess a number of risk. One risk area is Decompression Sickness (DCS) resulting from extravehicular activity (EVA) after exposure to habitat conditions. The proposed auto-focusing and steering ultrasonic TCD research tool will provide measurable DCS metrics and parameters to establish and model the level of risk due to these habitats & environments.

POTENTIAL NON-NASA COMMERCIAL APPLICATIONS (Limit 1500 characters, approximately 150 words)
Total mortality rates in severe trauma occurrences show that 90 percent die within the first hour. This non-invasive auto-focusing and steering TCD technology developed in this program will provide an aid to paramedics in evaluating a trauma patient on site and in real-time.


Form Printed on 08-01-05 13:52