NASA SBIR 2004 Solicitation

FORM B - PROPOSAL SUMMARY


PROPOSAL NUMBER:04-II B2.03-8663
PHASE-I CONTRACT NUMBER: NNJ05JD48C
SUBTOPIC TITLE:Understanding and Utilizing Gravitational Effects on Molecular Biology and for Medical Applications
PROPOSAL TITLE:Single Electron Transistor Platform for Microgravity Proteomics

SMALL BUSINESS CONCERN (Firm Name, Mail Address, City/State/Zip, Phone)
QUANTUM LOGIC DEVICES
7801 North Lamar, Suite B-161
Austin ,TX 78752 - 1017
(512) 302 - 5030

PRINCIPAL INVESTIGATOR/PROJECT MANAGER (Name, E-mail, Mail Address, City/State/Zip, Phone)
Louis   Brousseau
lou@quantumlogicdevices.com
7801 North Lamar, Suite B-161
Austin, TX  78752 -1017
(512) 302 - 5030

TECHNICAL ABSTRACT (Limit 2000 characters, approximately 200 words)
This Phase II program builds from the successful Phase I efforts to demonstrate that Quantum Logic Devices' nanoelectronic platform for biological detection could detect binding of Epo, TNF-alpha, IL-6, and IGF-1 in saline and serum without labels. The creation of an electronic "direct detection" platform for proteomics, enables rapid point of care monitoring of metabolic analytes in microgravity. This Phase II proposal will build working prototypes based on PDA-style electronic data capture with disposable assay cartridges for the analytes demonstrated in Phase I.

POTENTIAL NASA COMMERCIAL APPLICATIONS (Limit 1500 characters, approximately 150 words)
The product of this program is a handheld bioassay system that would be ideally suited for all biomedical research and diagnostic needs of current and future space missions. Real-time, quantitative monitoring of proteomic analytes will answer real questions about the metabolic and physiological changes induced by microgravity and space flight.

POTENTIAL NON-NASA COMMERCIAL APPLICATIONS (Limit 1500 characters, approximately 150 words)
This technology will be a key part of the rapidly emerging paradigm of telemedicine, and provide point of care diagnostics capabilities, which are the most rapidly growing segment of the medical testing market.


Form Printed on 08-01-05 13:52